![]() ![]() ![]() ![]() The protein misfolds in nerve cells (neurons) in the brain and spinal cord and causes the onset of MND symptoms. People with MND who have a SOD1 gene mutation are thought to produce a faulty SOD1 protein. Biogen have also revealed that they are conducting a new Phase 3 clinical trial of tofersen in those who have an SOD1 gene mutation but do not yet show symptoms of MND. Global biotechnology company Biogen has announced plans to make tofersen, a potential treatment for people whose MND is believed to be driven by mutations in the SOD1 gene, available to more people on an early access programme.
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